Two Miscarriages and Years of Infertility: Precision Immunotherapy Brings New Hope to a 34-Year-Old Woman

There are many causes of fertility difficulties in couples of childbearing age. Among them, infertility caused by immune abnormalities in the body, known as immune infertility, is receiving increasing attention.

Recently, at HeYou Hospital, Ms. Wang (pseudonym) received specialized treatment from the Department of Rheumatology and Immunology. Multiple abnormal immune indicators that could potentially affect conception were effectively controlled within two months, bringing new hope to her and her family.

The 34-year-old Ms. Wang was eager to welcome a new member to her family but suffered the blow of two miscarriages. Examinations revealed issues with her immune system. Undeterred, Ms. Wang came to HeYou Hospital with hope.

Following a multidisciplinary consultation between the Departments of Rheumatology and Immunology and Gynecology, Ms. Wang underwent relevant specialized examinations. The results showed multiple abnormal immune indicators, including antinuclear antibodies and ds-DNA antibodies, along with elevated IgG levels. Although she had no obvious physical symptoms, these indicators likely posed obstacles on her path to pregnancy. Having sought medical advice without success, Ms. Wang felt increasingly anxious.

Addressing Ms. Wang's urgency, Director Feng Xiugao of the Department of Rheumatology and Immunology developed a comprehensive treatment plan based on her specific condition. This plan included antiviral therapy, immunosuppression, dietary adjustments, immune function modulation, and daily precautions.

Under the professional guidance of the multidisciplinary team, Ms. Wang strictly adhered to medical advice and fully cooperated with the treatment. Two months of therapy yielded gratifying results: the antinuclear antibody titer significantly decreased, multiple antibody indicators turned negative, and IgG levels returned to normal. Director Feng Xiugao of the Department of Rheumatology and Immunology stated that while the decline in antibody indicators was expected, the rapid improvement was still a pleasant surprise.

Director Feng Xiugao pointed out that although Ms. Wang's immune abnormalities have improved, this does not mean the underlying causes of recurrent miscarriage have been eliminated. The situation is highly complex, and there are many causes of recurrent miscarriage. The ultimate outcome depends on whether she can conceive and whether the pregnancy progresses smoothly until the birth of a healthy baby. The improvement in immune abnormalities can only be considered an initial success. 

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Department of Rheumatology and Immunology  |  Feng Xiugao